' 
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
USERS' SCORE
Good
Based on 2 Reviews
8.2
Supplement Facts
Serving Size: 4 Capsules
Serving Per Container: 30
Amount Per Serving
%DV
Vitamin C (from culture of S. cerevisiae)
50 mg
56%
Vitamin D (as D3 from culture of S. cerevisiae)
40 mcg (1,600 IU)
200%
Vitamin K (from culture of S. cerevisiae)
120 mcg
100%
Calcium (naturally occurring from Algae)
1,100 mg
85%
Magnesium (from Algae and Dead Sea minerals)
357 mg
85%
Vitamin K (as K2 MK-7)
50 mcg
+
Strontium (naturally occurring from Algae)
3.8 mg
+
Boron (from Brown Rice Chelate)
3 mg
+
Silica (naturally occurring from Algae)
2.2 mg
+
Vanadium (naturally occurring from Algae)
25 mcg
+
Raw Probiotic & Enzyme BlendLipase, Protease, Aspergillopepsin, beta-Glucanase, Cellulase, Bromelain, Phytase, Lactase, Papain, Peptidase, Pectinase, Hemicellulase, Xylanase, [Lactobacillus bulgaricus, Lactobacillus plantarum] (500 Million CFU).
64 mg
+
Top Medical Research Studies
9.5
Calcium fosfomycin effective for UTIs
Pharmacokinetic/Pharmacodynamic Analysis of Oral Calcium Fosfomycin: Are Urine Levels Sufficient to Ensure Efficacy for Urinary Tract Infections?
High relevance to treatment efficacy
We explored the potential of calcium fosfomycin, a well-known antibiotic, in treating urinary tract infections (UTIs). Our focus was on how effectively it works when taken orally by healthy women. We dove into the drug’s urine concentration levels after administration, noting that about 18% of the drug is excreted through urine. This low level of excretion relates back to its poor oral absorption and reliance on the kidneys to filter it out.
By conducting a pharmacokinetic/pharmacodynamic analysis, we established thresholds for its effectiveness based on various dosage regimens. For a single dose of 500 mg, 1000 mg, and a schedule of 1000 mg every 8 hours for 3 days, we identified breakpoints of 8, 16, and 32 mg/L, respectively. Notably, our findings indicated that the chances of success for treating UTIs with the 1000 mg every 8 hours regimen are quite high—over 95%—given the susceptibility profile of the bacteria causing these infections.
Overall, our analysis confirms that using calcium fosfomycin in this manner can provide sufficient urine concentrations to effectively combat UTIs in women, supporting its continued use in this area.
By conducting a pharmacokinetic/pharmacodynamic analysis, we established thresholds for its effectiveness based on various dosage regimens. For a single dose of 500 mg, 1000 mg, and a schedule of 1000 mg every 8 hours for 3 days, we identified breakpoints of 8, 16, and 32 mg/L, respectively. Notably, our findings indicated that the chances of success for treating UTIs with the 1000 mg every 8 hours regimen are quite high—over 95%—given the susceptibility profile of the bacteria causing these infections.
Overall, our analysis confirms that using calcium fosfomycin in this manner can provide sufficient urine concentrations to effectively combat UTIs in women, supporting its continued use in this area.
Read More
8
Vitamin D linked to UTIs
The Association between Serum Vitamin D Levels and Urinary Tract Infection Risk in Children: A Systematic Review and Meta-Analysis.
Direct study on children
We set out to explore the connection between serum vitamin D levels and urinary tract infections (UTIs) in children. Our thorough investigation involved a systematic review and meta-analysis of various studies, including 12 case-control studies and a cross-sectional study. This comprehensive analysis incorporated data from a total of 839 children suffering from UTIs and 929 healthy controls.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Read More
8
Vitamin D deficiency linked to UTIs
The Association Between Vitamin D and Urinary Tract Infection in Children: A Case-Control Study.
Directly investigates vitamin D's effect
We set out to explore the link between vitamin D deficiency and urinary tract infections (UTIs) in children. Our research included a well-defined case-control study with children aged one to five years. We compared 82 children experiencing their first febrile UTI to 82 healthy peers.
By measuring vitamin D levels in their blood, we found that children suffering from UTIs had significantly lower levels of 25-hydroxy vitamin D. The average level in the UTI group was 24.27 ng/mL, while the control group had a healthier average of 31.97 ng/mL. Alarmingly, we discovered that 41.5% of the children with UTIs were vitamin D deficient compared to just 2.2% in the healthy group.
Our study indicates that low vitamin D levels may indeed be a risk factor for UTIs in young children. This finding sheds light on an important aspect of pediatric health that could lead to better prevention strategies for these infections.
By measuring vitamin D levels in their blood, we found that children suffering from UTIs had significantly lower levels of 25-hydroxy vitamin D. The average level in the UTI group was 24.27 ng/mL, while the control group had a healthier average of 31.97 ng/mL. Alarmingly, we discovered that 41.5% of the children with UTIs were vitamin D deficient compared to just 2.2% in the healthy group.
Our study indicates that low vitamin D levels may indeed be a risk factor for UTIs in young children. This finding sheds light on an important aspect of pediatric health that could lead to better prevention strategies for these infections.
Read More
Most Useful Reviews
7
No recurrence noted
I recommend this for men in their 40s. I bought it for my husband who has had urinary stones. I've been taking it regularly but haven’t noticed a significant effect. However, since starting it, I haven't experienced any recurrence of urinary stones.
Read More
6.3
Gastrointestinal comfort
This product doesn’t upset my stomach, unlike others I've tried that caused discomfort. It's a good alternative for those who can't tolerate chelate calcium. I can only manage to take 1-2 capsules per day, which may limit its effectiveness, but I haven’t noticed an increase in issues like white markings on my nails or teeth crumbling.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.3
- All Researches
9.5
Calcium fosfomycin effective for UTIs
Pharmacokinetic/Pharmacodynamic Analysis of Oral Calcium Fosfomycin: Are Urine Levels Sufficient to Ensure Efficacy for Urinary Tract Infections?
High relevance to treatment efficacy
We explored the potential of calcium fosfomycin, a well-known antibiotic, in treating urinary tract infections (UTIs). Our focus was on how effectively it works when taken orally by healthy women. We dove into the drug’s urine concentration levels after administration, noting that about 18% of the drug is excreted through urine. This low level of excretion relates back to its poor oral absorption and reliance on the kidneys to filter it out.
By conducting a pharmacokinetic/pharmacodynamic analysis, we established thresholds for its effectiveness based on various dosage regimens. For a single dose of 500 mg, 1000 mg, and a schedule of 1000 mg every 8 hours for 3 days, we identified breakpoints of 8, 16, and 32 mg/L, respectively. Notably, our findings indicated that the chances of success for treating UTIs with the 1000 mg every 8 hours regimen are quite high—over 95%—given the susceptibility profile of the bacteria causing these infections.
Overall, our analysis confirms that using calcium fosfomycin in this manner can provide sufficient urine concentrations to effectively combat UTIs in women, supporting its continued use in this area.
By conducting a pharmacokinetic/pharmacodynamic analysis, we established thresholds for its effectiveness based on various dosage regimens. For a single dose of 500 mg, 1000 mg, and a schedule of 1000 mg every 8 hours for 3 days, we identified breakpoints of 8, 16, and 32 mg/L, respectively. Notably, our findings indicated that the chances of success for treating UTIs with the 1000 mg every 8 hours regimen are quite high—over 95%—given the susceptibility profile of the bacteria causing these infections.
Overall, our analysis confirms that using calcium fosfomycin in this manner can provide sufficient urine concentrations to effectively combat UTIs in women, supporting its continued use in this area.
Read More
9
Calcium's role in UTI prevention
Non Clinical Model to Assess the Mechanism of Action of a Combined Hyaluronic Acid, Chondroitin Sulfate and Calcium Chloride: HA+CS+CaCl Solution on a 3D Human Reconstructed Bladder Epithelium.
Relevant to urinary infection treatments
We investigated how a combination of hyaluronic acid, chondroitin sulfate, and calcium chloride (collectively referred to as HA+CS+CaCl) could help in preventing urinary tract infections (UTIs). This study used a three-dimensional model of human bladder tissue to assess this solution’s effectiveness. Our focus was on how well it could inhibit bacterial growth, form protective films on bladder surfaces, and prevent bacterial adhesion and biofilm formation.
Our results indicated that HA+CS+CaCl showed promising properties in counteracting bacterial invasion. Specifically, the calcium in this combination played a role in this physico-mechanical mode of action. While we understand that isolating the effects of calcium alone is challenging, the overall findings suggest that this medical solution could offer a viable alternative to antibiotics for treating recurrent UTIs.
By reducing bacterial adherence to the bladder epithelium, HA+CS+CaCl might help in better managing and reducing infections. This approach can be particularly appealing, considering the rising concern over antibiotic resistance in treating UTIs.
Our results indicated that HA+CS+CaCl showed promising properties in counteracting bacterial invasion. Specifically, the calcium in this combination played a role in this physico-mechanical mode of action. While we understand that isolating the effects of calcium alone is challenging, the overall findings suggest that this medical solution could offer a viable alternative to antibiotics for treating recurrent UTIs.
By reducing bacterial adherence to the bladder epithelium, HA+CS+CaCl might help in better managing and reducing infections. This approach can be particularly appealing, considering the rising concern over antibiotic resistance in treating UTIs.
Read More
8
Vitamin D deficiency increases UTI risk
Association of Posttransplant Circulating 25-Hydroxyvitamin D and Late-Onset Infections Among Kidney Transplant Recipients: The Wisconsin Allograft Recipient Database (WisARD).
Highly relevant infection prevention study
We explored the link between vitamin D levels and late-onset urinary tract infections (UTIs) among kidney transplant recipients. Our study analyzed data from 2,207 individuals who had measurements of their vitamin D levels after transplantation.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
We found that lower levels of circulating vitamin D were associated with a higher risk of developing late-onset infections. Specifically, every time the vitamin D level dropped by 5 ng/mL, the risk of infection increased by 5%. This connection was notably stronger for urinary tract infections, particularly in male recipients, showing a more than twofold increase in risk for those with vitamin D deficiency.
These findings suggest that maintaining adequate vitamin D levels could be a valuable strategy in preventing infections after kidney transplants. However, further research, including clinical trials, will be crucial to determine a clear causal relationship between vitamin D and urinary tract infections.
Read More
8
Vitamin D's role in UTIs
Serum Vitamin D and Zinc Levels in Children with Urinary Tract Infection without Confounding Factors: A Case-Control Study.
Highly relevant to pediatric UTIs
We explored the relationship between vitamin D levels and urinary tract infections (UTIs) in children. In our study, we assessed the serum vitamin D and zinc levels among two groups: 40 healthy children and 40 children suffering from UTIs, ensuring that no other health factors influenced the results.
Our findings revealed a stark difference between the groups. A staggering 80% of the children with UTIs had vitamin D deficiency, compared to only 17.5% in the healthy group. This significant gap raised an interesting question: could low vitamin D levels contribute to the likelihood of developing UTIs in children?
We also noted that low zinc levels paralleled vitamin D deficiency, with 60% of UTI patients showing zinc insufficiency compared to just 17.5% in the healthy cohort. This observation suggests that both nutrients might be crucial for maintaining a healthy immune response, particularly in young children.
Overall, our study highlights the potential importance of addressing vitamin D levels in children prone to UTIs. Supplementing with vitamin D and zinc could become a vital strategy in not only treating infections but also preventing future occurrences.
Our findings revealed a stark difference between the groups. A staggering 80% of the children with UTIs had vitamin D deficiency, compared to only 17.5% in the healthy group. This significant gap raised an interesting question: could low vitamin D levels contribute to the likelihood of developing UTIs in children?
We also noted that low zinc levels paralleled vitamin D deficiency, with 60% of UTI patients showing zinc insufficiency compared to just 17.5% in the healthy cohort. This observation suggests that both nutrients might be crucial for maintaining a healthy immune response, particularly in young children.
Overall, our study highlights the potential importance of addressing vitamin D levels in children prone to UTIs. Supplementing with vitamin D and zinc could become a vital strategy in not only treating infections but also preventing future occurrences.
Read More
8
Vitamin D linked to UTIs
The Association between Serum Vitamin D Levels and Urinary Tract Infection Risk in Children: A Systematic Review and Meta-Analysis.
Direct study on children
We set out to explore the connection between serum vitamin D levels and urinary tract infections (UTIs) in children. Our thorough investigation involved a systematic review and meta-analysis of various studies, including 12 case-control studies and a cross-sectional study. This comprehensive analysis incorporated data from a total of 839 children suffering from UTIs and 929 healthy controls.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Through our analysis, we observed that children diagnosed with UTIs had notably lower levels of serum vitamin D when compared to healthier counterparts. The findings indicated that low vitamin D levels were indeed associated with a higher likelihood of experiencing a UTI, with a significant increase in this risk for children whose vitamin D levels fell below 20 ng/mL. Specifically, children with vitamin D levels under this threshold had a much higher risk of developing UTIs.
Overall, our review strengthens the case for considering vitamin D levels as a potential risk factor in urinary tract infections among children, especially when those levels drop below the critical point.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
7
No recurrence noted
I recommend this for men in their 40s. I bought it for my husband who has had urinary stones. I've been taking it regularly but haven’t noticed a significant effect. However, since starting it, I haven't experienced any recurrence of urinary stones.
6.3
Gastrointestinal comfort
This product doesn’t upset my stomach, unlike others I've tried that caused discomfort. It's a good alternative for those who can't tolerate chelate calcium. I can only manage to take 1-2 capsules per day, which may limit its effectiveness, but I haven’t noticed an increase in issues like white markings on my nails or teeth crumbling.
Read More
